Analysis of the Killing Activity of Immune Cells with Tumor Organoids

Abstract

The tumor microenvironment (TME) is considered a key factor in the occurrence and development of tumors. It not only exists and affects the structure, function, and metabolism of the tissue where the tumor is located, but also relates to the intrinsic environment of the tumor cells themselves. Positive responses to immunotherapy often depend on the interaction between tumor cells and the immunoregulation within the TME. Under these interactions, the TME plays a significant role in either suppressing or enhancing immune responses. However, there are currently no mature research methods for characterizing or modeling the TME.